Dehong's economy is uniquely shaped by its border location. Cross-border trade with Myanmar is the economic backbone, with the Ruili-Jiegao area serving as a major trading hub for jade, timber, agricultural products, and consumer goods. China's largest jade trading market is located in Ruili, processing and trading jade from Myanmar.
Agriculture thrives in the tropical climate. Dehong produces rubber, sugarcane, coffee, tea, and tropical fruits including durian, mangosteen, and dragon fruit. The region is one of China's few areas where coffee is grown commercially.
Tourism is growing rapidly, driven by Dehong's unique cultural attractions and tropical scenery. The exotic border atmosphere, Dai culture, and relatively low tourist numbers compared to other Yunnan destinations make it increasingly popular.
Light manufacturing, particularly in textiles and food processing, contributes to the local economy. The prefecture also has significant hydropower resources from the Ruili River and its tributaries. Dehong's GDP reached approximately 60 billion yuan.