Luzhou's history as a settlement dates back over 2,000 years. Its strategic location at the Yangtze-Tuo River confluence made it an important port and trading center from early times.
The most significant chapter in Luzhou's history began in 1573 during the Ming Dynasty, when the first fermentation pits were dug for what would become Luzhou Laojiao. These pits have been in continuous use ever since, making them the oldest active fermentation pits in the world.
During the mid-1930s, Luzhou played a notable role. Military forces crossed the Chishui River four times in the region, and Taiping Ancient Town preserves many historical sites from this period.
In the modern era, Luzhou has developed into a major industrial center. While baijiu production remains its signature industry, the city has diversified into chemicals, machinery manufacturing, and port logistics.